[1]金浪 石洁 黄正 贾永伟 张建坡 魏礼成 金昊雷.3D打印数字技术辅助PVP治疗胸腰椎多节段骨质疏松性椎体压缩性骨折的临床研究[J].中华老年骨科与康复电子杂志,2026,(02):65-71.[doi:10.3877/cma.j.issn.2096-0263.2026.02.001]
　Jin Lang,Shi Jie,Huang Zheng,et al.Clinical study of 3D printing digital technique assisted with PVP in the treatment of multi-segmental osteoporotic vertebral compression fractures of thoracolumbar vertebrae[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2026,(02):65-71.[doi:10.3877/cma.j.issn.2096-0263.2026.02.001]
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3D打印数字技术辅助PVP治疗胸腰椎多节段骨质疏松性椎体压缩性骨折的临床研究()
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中华老年骨科与康复电子杂志[ISSN:1674-3911/CN:11-9292/R]

卷:
期数:
2026年02期
页码:
65-71
栏目:
骨质疏松
出版日期:
2026-04-05

文章信息/Info

Title:
Clinical study of 3D printing digital technique assisted with PVP in the treatment of multi-segmental osteoporotic vertebral compression fractures of thoracolumbar vertebrae
作者:
金浪1 石洁2 黄正1 贾永伟1 张建坡1 魏礼成1 金昊雷3
200052 上海中医药大学附属光华医院 上海市中医药研究院中西医结合关节炎研究所脊柱外科1 ，放射科2；200052 上海市虹口区江湾镇街道社区卫生服务中心西医全科3
Author(s):
Jin Lang1;  Shi Jie2;  Huang Zheng1;  Jia Yongwei1;  Zhang Jianpo1;  Wei Licheng1;  Jin Haolei3.
1Department of Spine Surgery, 2Department of Radiology, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine. Arthritis Institute of integrated Traditional Chinese and Western Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai 200052, China; 3General Department of Western Medicine, Jiangwan Town Street Community Health Service Center of Shanghai Hongkou District, Shanghai 200052, China
关键词:
3D打印技术;  PVP;  OVCF;  疗效;  骨水泥渗漏
Keywords:
3D printing technology;  PVP;  OVCF;  Effect;  Bone cement leakage
DOI:
10.3877/cma.j.issn.2096-0263.2026.02.001
文献标志码:
A
摘要:
目的 探讨3D打印数字技术辅助经皮穿刺椎体成形术（PVP）治疗胸腰椎多节段骨质疏松性椎体压缩性骨折（OVCF）的临床研究。方法 选取2017年2月至2020年3月于我院骨科进行治疗的114例OVCF患者纳入研究，其中观察组56例行3D打印技术+PVP术式治疗，对照组58例行PVP治疗。比较两组患者的性别、年龄、病程、骨密度、骨折部位、骨折类型、骨水泥注射量、椎体压缩程度、终板/后壁是否完整。记录不同骨折类型患者的穿刺定位时间和透视次数。分别于术前、术后1 d和术后12个月测定患者的疼痛评分、功能评分和影像学指标。统计随访期间发生骨水泥渗漏、神经损伤等并发症发生情况。根据骨水泥渗漏情况，将所有患者分为渗漏组和未渗漏组，并比较两组患者的一般临床资料，将治疗术式纳入和剔除分别建立影响患者骨水泥渗漏的多因素Logistic回归模型，并利用受试者工作特征曲线（ROC）评价模型区分度，利用Bootstrap重复取样的方法进行内部验证。结果 与术前比较，术后12个月，两种不同术式患者的椎体平均高度均明显升高，Cobb角、Oswestry功能障碍指数（ODI）、椎体压缩比、视觉模拟评分（VAS）均明显降低；差异有统计学意义（P＜0.05）。术后12个月，两组患者均未出现神经功能损伤及卧床相关并发症；术后观察组发生骨水泥渗漏概率明显低于对照组（χ2=13.259，P＜0.001）。椎体压缩程度、骨水泥注射量、治疗术式、终板/后壁完整是术后发生骨水泥渗漏的影响因素（P＜0.05）。纳入治疗术式的模型具有更高的预测价值。结论 3D打印技术联合PVP术有效改善OVCF患者术中透视次数和穿刺时间，改善术后ODI和VAS评分，降低骨水泥渗漏率。
Abstract:
Objective To explore the clinical study of 3D printing digital technique assisted with PVP in the treatment of multi-segmental osteoporotic vertebral compression fractures of thoracolumbar vertebrae. Methods A total of 114 patients with OVCF who were treated in the department of orthopaedics in our hospital from February 2017 to March 2020 were enrolled in the study. Patients of the observation group (n=56) were treated with 3D printing technique and PVP operation, and patients in the control group (n=58) were treated with PVP. The sex, age, course of disease, bone mineral density, bone cement injection volume, fracture site, fracture type, vertebral compression degree and integrity of endplate/posterior wall were compared between the two groups. The puncture location time and fluoroscopy times of patients with different fracture types were recorded. The pain score, function score and imaging index were measured before operation, 1 day and 12 months after operation. The complications such as bone cement leakage and nerve injury were counted during the follow-up period. According to the situation of bone cement leakage, all patients were divided into non-leakage group and leakage group, and the general clinical data of the two groups were compared. the multi-factor Logistic regression models affecting bone cement leakage were established respectively, and the model differentiation was evaluated by ROC, and the internal verification was carried out by the method of Bootstrap repeated sampling. Results Compared with those of the control group, the average vertebral body height of the two groups increased significantly at 1 day and 12 months after operation, while the vertebral compression ratio, VAS score, Cobb angle and ODI score decreased significantly, and the VAS score and ODI at 12 months after operation were significantly lower than those at 1 day after operation(P<0.05). 12 months after operation, there was no neurological injury and bedridden-related complications in both groups; bone cement leakage occurred in 5 patients (9.00%) of the observation group and 22 patients (37.93%) of the control group. There was significant difference in bone cement leakage between the two groups (χ2=13.259, P<0.001). The amount of bone cement injected, the degree of vertebral compression, the integrity of endplate/posterior wall and the mode of treatment were the influencing factors of bone cement leakage (P<0.05). The model incorporated into the therapeutic technique has higher predictive value. Conclusions 3D printing technique combined with PVP can reduce the intraoperative puncture time and fluoroscopy times of OVCF, especially flat and double concave fractures, improve the postoperative VAS and ODI.

备注/Memo

备注/Memo:
基金项目：上海市长宁区科学技术委员会项目（NKW2018Y13）
更新日期/Last Update: 2026-05-19