[1]张禄锴,马剑雄,李风波,等.双膦酸盐类药物治疗骨质疏松症的研究进展[J].中华老年骨科与康复电子杂志,2017,(03):184-187.[doi:10.3877/cma.j.issn.2096-0263.2017.03.010]
 Zhang Lukai,Ma JianXiong,Li Fengbo,et al.The research development of bisophosphonates in the treatment of osteoporosis[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2017,(03):184-187.[doi:10.3877/cma.j.issn.2096-0263.2017.03.010]
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双膦酸盐类药物治疗骨质疏松症的研究进展()
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中华老年骨科与康复电子杂志[ISSN:1674-3911/CN:11-9292/R]

卷:
期数:
2017年03期
页码:
184-187
栏目:
综述
出版日期:
2017-06-01

文章信息/Info

Title:
The research development of bisophosphonates in the treatment of osteoporosis
作者:
张禄锴 12马剑雄 1李风波 3马信龙 3
300211 天津市天津医院骨科研究所 1;300193 天津中医药大学研究生院 2;300142 天津市天津医院 3
Author(s):
Zhang Lukai Ma JianXiong Li Fengbo Ma XinLong
1Tianjin institute of integrated traditional and western medicine orthopedic, Tianjin 300211, China; 2Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China; 3Tianjin Hospital, Tianjin 300142, China
关键词:
双膦酸盐 骨质疏松症 治疗结果
Keywords:
Bisphosphonates Osteoporosis Treatment outcome
DOI:
10.3877/cma.j.issn.2096-0263.2017.03.010
文献标志码:
A
摘要:
骨质疏松症是一种以骨密度减小,骨折风险增加为特征的全身代谢性疾病。骨质疏松症的治疗方法一直是研究热点,其中双膦酸盐类药物作为一线的抗骨质疏松药物,对治疗骨质疏松症起着重要的作用。本文将围绕双膦酸盐类抗骨质疏松药物的发展、作用机理、疗效方面展开综述,为今后的研究提供参考。
Abstract:
Osteoporosis is a systemic metabolic osteopathy characterized by low bone mineral density, leading to an increased risk of fractures. The treatment of osteoporosis is a research hotspot nowadays, and bisphosphonate as a first- line drug plays a important role in the treatment of osteoporosis. This paper systematically reviews current research progress of bone resorption inhibitive bisphosphonate, mechanism and clinical effectiveness, which may provide some references for future research.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金项目(81572154)天津市卫生局科技攻关项目(15KG123);卫生部医药卫生科技发展研究中心(W2013ZT058)
更新日期/Last Update: 2017-06-01