[1]张勇刚,贺翠琴,张欢.IVIM-DWI-MRI对强直性脊柱炎骶髂关节病变活动性的评估价值[J].中华老年骨科与康复电子杂志,2022,(03):147-151.[doi:10.3877/cma.j.issn.2096-0263.2022.03.004]
　Zhang Yonggang,He Cuiqin,Zhang Huan..The value of IVIM-DWI-MRI in the evaluation of sacroiliac joint activity in ankylosing spondylitis[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2022,(03):147-151.[doi:10.3877/cma.j.issn.2096-0263.2022.03.004]
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IVIM-DWI-MRI对强直性脊柱炎骶髂关节病变活动性的评估价值()
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中华老年骨科与康复电子杂志[ISSN:1674-3911/CN:11-9292/R]

卷:
期数:
2022年03期
页码:
147-151
栏目:
脊柱专题
出版日期:
2022-06-05

文章信息/Info

Title:
The value of IVIM-DWI-MRI in the evaluation of sacroiliac joint activity in ankylosing spondylitis
作者:
张勇刚1; 贺翠琴1; 张欢2
430100 武汉市协和江北医院/蔡甸区人民医院放射科1；435000 鄂东医疗集团黄石市中医医院骨科2
Author(s):
Zhang Yonggang1;  He Cuiqin1;  Zhang Huan2.
1Department of Radiology in Wuhan Xiehe Jiangbei hospital/Caidian District People’s Hospital; 2Department of Orthopaedics in Huangshi traditional Chinese Medicine Hospital of Edong medical group2
Keywords:
Incoherent motion diffusion-weighted;  Agnetic resonance imaging;  Ankylosing spondylitis;  Sacroiliac joint disease
DOI:
10.3877/cma.j.issn.2096-0263.2022.03.004
文献标志码:
A
摘要:
目的 探讨体素内不相干运动扩散加权成像（IVIM-DWI）-磁共振成像（MRI）对强直性脊柱炎（AS）骶髂关节病变活动性的评估价值。方法 选取2018年3月至2021年3月本院AS患者128例作为AS组，男68例、女60例，平均年龄（31±9）岁，依据巴氏AS疾病活动指数（BASDAI）分为活动组（n=42）和稳定组（n=86），同期选取体检健康人员50例作为健康组，采用IVIM-DWI-MRI检测纯水分子扩散系数（D）、灌注相关伪扩散系数（D*）、灌注分数（f），比较各组D、D*、f，分析IVIM-DWI-MRI对AS骶髂关节病变活动性的评估价值。结果 AS组D、D*、f高于健康组，差异有统计学意义（P＜0.05）；活动组D、D*、f高于稳定组，差异有统计学意义（P＜0.05）；ROC曲线显示，在评估AS骶髂关节病变活动性的敏感度、特异度、曲线下面积中，D为76.19 %、79.07 %、0.817，D*为66.67 %、72.09 %、0.765，f为71.43 %、74.42 %、0.803，D、D*、f联合时为95.24 %、93.02 %、0.905，D、D*、f联合高于单独D、D*、f，差异有统计学意义（P＜0.05）。结论 IVIM-DWI-MRI中D、D*、f等指标与AS骶髂关节病变活动性变化有关，可作为评估指标，且D、D*、f联合时的评估价值更高。
Abstract:
Objective To discuss the value of incoherent motion diffusion-weighted imaging (IVIM-DWI)-magnetic resonance imaging (MRI) in the evaluation of sacroiliac joint activity in ankylosing spondylitis (AS). Methods The 128 patients with AS in our hospital from March 2018 to March 2021 were selected as the AS group, which were divided into active group (n=42) and stable group (n=86) according to the Basdai disease activity index (BASDAI), and the 50 healthy persons were selected as the healthy group during the same period. The pure water molecular diffusion coefficient (D), perfusion-related pseudo diffusion coefficient (D*) and perfusion-related fraction (F) were detected by IVIM-DWI-MRI, and the D, D* and F of the each groups were compared, the evaluation value of IVIM-DWI-MRI on the sacroiliac joint disease activity of AS were analyzed. Results The D, D* and F in AS group were higher than those in healthy group, the difference was statistically significant (P<0.05). The D, D* and F in the activity group were higher than those in the stable group, the difference was statistically significant (P<0.05). The ROC curve shows that, in the sensitivity, specificity, and area under the curve for assessing the sacroiliac joint activity of AS, the D were 76.19%, 79.07% and 0.817; the D* were 66.67%, 72.09%, 0.765; the F were 71.43%, 74.42% and 0.803; The combined values of D, D* and F were 95.24%, 93.02% and 0.905, the combined values of D, D* and F were higher than those of D, D* and F alone, the difference was statistically significant (P<0.05). Conclusions The D, D*, F and other indexes in IVIM-DWI-MRI are related to the changes of the sacroiliac joint lesion activity, which can be used AS evaluation indexes, and the combined evaluation value of D, D*, F is higher.

备注/Memo

备注/Memo:
基金项目：湖北省卫建委2019年度第三批联合基金（WJ2019 H486）
更新日期/Last Update: 2022-08-03