[1]崔红旺,蒋电明.骨细胞程序性死亡在骨质疏松中作用的研究进展[J].中华老年骨科与康复电子杂志,2016,(03):181-184.[doi:10.3877/cma.j.issn.2096-0263.2016.03.011]
　Cui Hongwang,Jiang Dianming.Effect of the programmed cell death of osteocyte on osteoporosis[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2016,(03):181-184.[doi:10.3877/cma.j.issn.2096-0263.2016.03.011]
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骨细胞程序性死亡在骨质疏松中作用的研究进展()
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中华老年骨科与康复电子杂志[ISSN:1674-3911/CN:11-9292/R]

卷:
期数:
2016年03期
页码:
181-184
栏目:
综述
出版日期:
2016-08-05

文章信息/Info

Title:
Effect of the programmed cell death of osteocyte on osteoporosis
作者:
崔红旺; 蒋电明
400016 重庆医科大学附属第一医院骨科
Author(s):
Cui Hongwang;  Jiang Dianming
Department of Orthopaedics, First Affliated Hospital of Chongqing University of Medical Sciences, Chongqing 400016, China
关键词:
骨质疏松症; 　骨细胞; 　凋亡; 　自噬; 　程序性坏死
Keywords:
Osteoporosis;  Osteocytes;  Apoptosis;  Autophagy;  Necroptosis
DOI:
10.3877/cma.j.issn.2096-0263.2016.03.011
文献标志码:
A
摘要:
骨质疏松症（osteoporosis， OP）是一个全球公共健康问题，其发病机制尚未完全阐明。近年来研究发现骨细胞过度死亡在 OP 的发病过程中起着重要的作用。随着人类对细胞死亡方式的不断认识，发现除凋亡以外，自噬和程序性坏死也被认为是细胞程序性死亡的方式。本文就骨细胞的这三种程序性死亡方式在 OP 发病机制中的作用进行综述。
Abstract:
Osteoporosis is a global public health problem, the pathogenesis has not been fully elucidated yet. Osteocytes play a crucial role in the pathophysiological process of osteoporosis. Along with constantly understanding of cell death forms, autophagy and necroptosis are regarded as the other modes of programmed cell death besides apoptosis. This article reviews the roles of the three forms of cell death in the pathogenesis of osteoporosis.

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备注/Memo

备注/Memo:
基金项目：国家自然科学基金（81171685）
更新日期/Last Update: 2017-04-01