[1]张超,王国文,韩秀鑫,等.肿瘤型假体置换治疗老年股骨上段转移瘤的疗效分析[J].中华老年骨科与康复电子杂志,2017,(06):332-335.[doi:10.3877/cma.j.issn.2096-0263.2017.06.003]
　Zhang Chao,Wang Guowen,Han Xiuxin,et al.The analysis of the surgical of tumor prosthetic replacement effect on treating elder patients with proximal femur metastasis[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2017,(06):332-335.[doi:10.3877/cma.j.issn.2096-0263.2017.06.003]
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肿瘤型假体置换治疗老年股骨上段转移瘤的疗效分析()
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中华老年骨科与康复电子杂志[ISSN:1674-3911/CN:11-9292/R]

卷:
期数:
2017年06期
页码:
332-335
栏目:
论著
出版日期:
2017-11-27

文章信息/Info

Title:
The analysis of the surgical of tumor prosthetic replacement effect on treating elder patients with proximal femur metastasis
作者:
张超; 王国文; 韩秀鑫; 李丽丽; 卢凤
300060 天津医科大学肿瘤医院骨与软组织肿瘤科
Author(s):
Zhang Chao; Wang Guowen;  Han Xiuxin;  Li Lili;  Lu Feng
Department of Bone and Soft Tissue Tumor, Tianjin Medical University Cancer Institute & Hospital, Tianjin 300060, China
关键词:
股骨;  转移瘤;  外科手术;  肿瘤型假体
Keywords:
Femur;  Metastatic tumor;  Surgical procedures;  operative;  Tumor prosthesis
DOI:
10.3877/cma.j.issn.2096-0263.2017.06.003
文献标志码:
A
摘要:
目的 分析肿瘤型假体置换治疗老年股骨上段转移瘤的临床疗效。方法 回顾性分析 2010 年 4 月至 2013 年 4 月天津医科大学肿瘤医院收治的符合手术标准的老年股骨上段转移瘤患者 31 例，其中男性 14例，女性 17例；年龄 65～73岁，平均（67±3）岁。所有患者均行肿瘤型假体置换，采用疼痛视觉模拟评分（VAS）于术前、术后 6个月对患者疼痛情况进行评估，采用 Enneking肢体恶性肿瘤保肢术后功能评分和 Harris评分对患者术后功能改善情况进行评估。结果 所有患者均顺利完成手术。术后随访时间 6～36个月，平均（11±3）个月，生存期 12.6个月。手术平均用时（71±9）min，术中平均出血量为（680±122）ml。术后 6个月 VAS评分（[ 2.7±0.3）分]较术前（[ 7.2±0.3）分]显著降低，差异有统计学意义（t=4.311，P＜0.05）。术后 6个月按照 Enneking肢体恶性肿瘤保肢术后功能评分：优 14例，良 13例，中 4例，优良率为 87.1%。术后 6 个月 Harris 评分为（79±4）分，较术前（[ 19±5）分]明显改善，差异有统计学意义（t=3.711，P＜0.05）。结论 对于存在病理性骨折或有高病理性骨折风险的老年患者采用肿瘤型假体置换治疗老年股骨上段转移癌，可获得良好临床疗效。
Abstract:
Objective To evaluate the surgical effect of tumor prosthetic replacement on treating elder patients with proximal femur metastasis. Methods Based on the inclusion and exclusion criteria, a retrospective study was performed among the selected 31 patients who underwent prosthetic replacement from April 2010 to April 2013. There were 14 males and 17 females involved. The average age of patients was 67± 3years. VAS score was evaluated pre- and 6 month post- operatively. Enneking score and Harris were evaluated for assessing the post-operative functional improvements. Results All surgeries were successfully performed. All cases were followed up for 6 to 36 months, with an average of 11±3 months, the expected lifetime was 12.6 months. The average surgical time was 71±9 min, and the average intra-operative blood loss was 680±122 ml. The pre-operative VAS score was 7.2±0.3 which was significantly decreased to postoperative 2.7±0.3 (t=4.311, P<0.05). Enneking score suggested the satisfactory rate was 87.1% as 14 excellent, 12 good and 4 moderate. The Harris score at post- operative 6 month was 79 ± 4 which was increased significantly compared to the preoperative score 19±5 (t=3.711, P＜0.05). Conclusion The tumor prosthesis replacement is an effective treatment for elder patients with proximal femur metastasis, especially for those with pathological fracture or with high-risk occurrence of pathological fractures.

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备注/Memo

备注/Memo:
基金项目：国家肿瘤临床医学研究中心项目资助，国家自然科学基金（81602363，81702161），天津市自然科学基金（17JCQNJC11000），天津医科大学自然科学基金（2016KYZQ10）
更新日期/Last Update: 2017-11-24