[1]陆惠根,黄鑫,张中伟,等.肺癌脊柱转移瘤的手术疗效分析[J].中华老年骨科与康复电子杂志,2018,(01):14-19.[doi:10.3877/cma.j.issn.2096-0263.2018.01.004]
　Lu Huigen,Huang Xin,Zhang Zhongwei,et al.The curative effect of surgical treatment for spinal metastases of lung cancer[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2018,(01):14-19.[doi:10.3877/cma.j.issn.2096-0263.2018.01.004]
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肺癌脊柱转移瘤的手术疗效分析()
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中华老年骨科与康复电子杂志[ISSN:1674-3911/CN:11-9292/R]

卷:
期数:
2018年01期
页码:
14-19
栏目:
骨肿瘤
出版日期:
2018-01-31

文章信息/Info

Title:
The curative effect of surgical treatment for spinal metastases of lung cancer
作者:
陆惠根1; 2; 黄鑫1; 张中伟2; 叶招明1
310009 浙江大学医学院附属第二医院骨科1；314000 嘉兴市第二医院骨科2
Author(s):
Lu Huigen 1; 2;  Huang Xin1;  Zhang Zhongwei2;  Ye Zhaoming1.
1 Department of Orthopaedics, The Second Affiliated Hospital of Zhejiang University, Hangzhou 310009, China; 2 Department of Orthopaedics, The Second Hospital of Jiaxing, Jiaxing 314000, China
关键词:
脊柱;  肺癌;  肿瘤转移;  外科手术
Keywords:
Spine;  Lung neoplasms;  Neoplasma metastasis;  Surgal procedures;  operative
DOI:
10.3877/cma.j.issn.2096-0263.2018.01.004
文献标志码:
A
摘要:
目的 探讨肺癌脊柱转移瘤的手术治疗效果。方法 回顾性分析2012年1月至2016年5月在浙江大学附属第二医院骨肿瘤中心及浙江省嘉兴市第二医院骨科住院治疗且病理诊断明确的肺癌脊柱转移瘤患者72例。其中男性48例（66.7%），女性24例（33.3%），平均年龄（61±4）岁，39例（54.2%）术前生存期评分为6分，27例（37.5%）7分，6例（8.3%）8分。随访并比较患者手术前后疼痛视觉模拟评分（VAS）及Frankel分级变化情况，评价手术疗效。结果 65例患者获得满意随访（90.2%）。随访时间6～12个月，平均（8.5±1.6）个月，VAS评分由术前（5.9±1.1）分降至术后（2.7±1.2）分，差异有统计学意义（t=21.24，P＜0.05）。术后Frankel分级明显改善，差异有统计学意义（Z=-4.978，P＜0.05），42例术前有神经功能障碍者5例未恢复，37例部分恢复，差异有统计学意义（Z=-4.978，P＜0.05）。结论 手术治疗肺癌脊柱转移瘤可有效缓解患者疼痛程度，改善神经功能。
Abstract:
Objective To investigate the curative effect of surgical treatment for spinal metastases of lung cancer. Methods A retrospective study was performed in 72 cases of spinal metastases of lung cancer treated in The Second Affiliated Hospital of Zhejiang University and The Second Hospital of Jiaxing. There were 48 males (66.7%) and 24 females (33.3%) with an average age of 61±4 years. The preoperative survival score were evaluated and 39 cases (54.2%) were 6 points, 27 cases (37.5%) were 7 points and 6 cases (8.3%) were 8 points. The Visual Analogue Scale (VAS) score and Frankel classification of two group were compared before and after surgery. Results Sixty-five patients (90.2%) were followed-up with a timespan of 6-12 months (8.5±1.6 months on the average). The VAS score decreased to (2.7±1.2) from preoperatively (5.9±1.1), with statisticl significance (t=21.24, P<0.05). The postoperative Frankel score was significantly improved, with statisticl significance (Z=-4.978, P<0.05). 5 patients among 42 cases with neurological deficit were not improved, 37 cases were partially recovered (Z=-4.978, P<0.05). Conclusion Surgical treatment can relieve the pain and improve the neurological function of patients with spinal metastases of lung cancer.

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更新日期/Last Update: 2018-01-31