同种异体肌腱在运动系统常见损伤中的应用-中华老年骨科与康复电子杂志

文章信息/Info

Title:: Application of tendon allografts in common injuries of the movement system

作者:: 谢志涛1; 4; 高小康1; 王丽敏2; 张净宇3; 李文静2; 高冰2; 胡永成1; 300000 天津医科大学1；101100 北京威达峰医学生物材料有限责任公司2；300000 天津市天津医院骨与软组织肿瘤科3；056500 邯郸，河北工程大学附属医院骨科中心4

Author(s):: Xie Zhitao1; 4; Gao Xiaokang1; Wang Limin2; Zhang Jingyu3; Li Wenjing2; Gao Bing2; Hu Yongcheng1; 1Tianjin Medical University, Tianjin 300000, China; 2Beijing Wonderful Medical Biomaterials Co., Ltd, Beijing 101100, China; 3Department of Bone and Soft Tissue Oncology, Tianjin Hospital, Tianjin 300000, China; 4Department of Orthopedics, Affiliated Hospital of Hebei Engineering University, Handan 056500, China

摘要:: 肌腱是连接肌肉和骨骼的致密结缔组织，有着高机械强度、良好的柔韧性及最佳弹性水平。肌腱主要功能是传递肌肉收缩产生的力量，使骨骼移动从而产生身体各部位的动作。然而在运动过程中，负荷超出肌腱的承受能力，或由于反复运动造成的累积磨损，肌腱会受到损伤。临床上常用的肌腱移植物有三类：自体肌腱、异体肌腱和人工合成材料移植物。理想的肌腱移植物应具备重塑肌腱的解剖特性、与原肌腱具有相似的生物力学特性、良好的组织相容性和尽可能少的并发症等特点。由于无供区损伤、手术时间短、麻醉时间短、使用止血带时间短、移植物尺寸多样化、手术切口少、术后疼痛轻等多种优势，同种异体肌腱在临床上正逐渐普遍地应用于运动系统损伤的修复。为了科学、有效地进行同种异体肌腱的研究及应用，本文综述了同种异体肌腱在运动医学中的研究进展及应用的文献，从而推动同种异体肌腱在运动系统损伤修复中的基础研究及临床应用。

Abstract:: Tendons are dense connective tissues that connect muscles to bones, providing high mechanical strength, goodflexibility, and optimal elasticity. The primary function of tendons is to transmit the force generated by muscle contractions, enabling movement of the skeleton and various body actions. However, during physical activity, tendons can become damaged due to loads exceeding their capacity or cumulative wear and tear caused by repetitive movements. In clinical practice, there are three main types of tendon grafts used: autografts, allografts, and synthetic materials. An ideal tendon graft should possess anatomical characteristics for tendon remodeling, similar biomechanical properties to the original tendon, good tissue compatibility, and minimal complications. Due to several advantages such as no donor site damage, shorter surgery and anesthesia times, shorter tourniquet use, diverse graft sizes, fewer incisions, and reduced postoperative pain, allogeneic tendon grafts are gradually being widely used for the repair of sports medicine system injuries. To advance the scientific and effective research and application of allogeneic tendon grafts, this review summarizes the research progress and application of allogeneic tendon grafts in sports medicine, aiming to promote the basic research and clinical application of allogeneic tendon grafts in the repair of movement system injuries.