[1]宋婷婷,王新民,毕希乐,等.老年髋部骨折围术期心力衰竭的危险因素分析[J].中华老年骨科与康复电子杂志,2018,(01):23-28.[doi:10.3877/cma.j.issn.2096-0263.2018.01.006]
 Song Tingting,Wang Xinmin,Bi Xile,et al.Analysis of risk factors of perioperative heart failure in elderly patients with hip fracture[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2018,(01):23-28.[doi:10.3877/cma.j.issn.2096-0263.2018.01.006]
点击复制

老年髋部骨折围术期心力衰竭的危险因素分析()
分享到:

中华老年骨科与康复电子杂志[ISSN:1674-3911/CN:11-9292/R]

卷:
期数:
2018年01期
页码:
23-28
栏目:
髋部骨折合并心力衰竭
出版日期:
2018-01-31

文章信息/Info

Title:
Analysis of risk factors of perioperative heart failure in elderly patients with hip fracture
作者:
宋婷婷1王新民2毕希乐1国强华1贾红丹1崔蕊1刘丽1
066000 秦皇岛市第一医院心血管内科1,骨科2
Author(s):
Song Tingting1 Wang Xinmin2 Bi Xile1 Guo Qianghua1 Jia Hongdan1 Cui Rui1 Liu Li1
1Department of Cardiology, 2Department of Orthopaedics, First hospital of Qin huangdao, Qin huangdao 066000, China
关键词:
老年人 髋骨折 围手术期 心力衰竭
Keywords:
Aged Hip fractures Perioperative period Heart failure
DOI:
10.3877/cma.j.issn.2096-0263.2018.01.006
文献标志码:
A
摘要:
目的 探讨老年髋部骨折患者围手术期发生心力衰竭的相关危险因素。方法 回顾性分析2010年10月至2017年1月因髋部骨折于秦皇岛市第一医院住院治疗的225例患者,其中心衰组64例、非心衰组161例,记录并比较两组患者的基本情况、相关检查结果及术中、术后管理因素等,采用多因素Logistic回归分析老年髋部骨折围手术期发生心力衰竭的相关危险因素。结果 心衰组与非心衰组在年龄、收缩压、入院至手术时间、ASA分级、系统疾病数超过4种、合并心血管疾病、低血红蛋白量、手术方式、输血量≥400 ml、术中补液量大、每日液体出入量差值大、输注血白蛋白、术后电解质紊乱等方面具有统计学差异(c2=19.861,c2=7.075,c2=8.732,c2=25.504,c2=29.226,c2=45.825,c2=14.362,c2=6.662,c2=8.190,c2=7.216,c2=30.086,c2=10.122,c2=12.079,均P<0.05)。Logistic回归分析示系统疾病数超过4种、合并心血管疾病、低血红蛋白量、电解质紊乱、围手术期液体“正平衡”、ASA分级Ⅱ级以上为老年髋部骨折患者围手术期发生心力衰竭的独立危险因素(OR:5.769,95% CI:1.212~36.243;OR:9.576,95% CI:2.118~45.387;OR:3.686,95% CI:1.313~10.349;OR:6.584,95% CI:1.217~26.744;OR:14.114,95% CI:5.021~42.342;OR:6.012,95% CI:3.245~11.329)。结论 老年髋部骨折围手术期发生心力衰竭是由多种因素共同作用的结果,围手术期准确的风险评估、早期治疗合并症、减少手术创伤以及完善术后补液是减少此类患者发生心力衰竭的关键。
Abstract:
Objective To analyze risk factors of the perioperative heart failure following hip fracture surgery in the aged patients and put forward prevention countermeasures so as to reduce the mortality rate for clinical work. Methods The present study included 225 elderly patients who had received hip fracture surgeries from October 2010 to January 2017 in our hospital. Patients were divided into heart failure group (64 cases) and non-heart failure group (161 cases). Single factor analysis was performed in three aspects as preoperative basic situation, preoperative examination and surgical management, the dominant risk factors then rolled into logistic regression analysis to conclude the dependent risk factors of perioperative heart failure. Results Age, systolic blood pressure, delay from admission to operation, ASA classification, numbers of systemic diseases (expect cardiovascular disease), cardiovascular disease, low hemoglobin volume, operative management, blood transfusion ≥400 ml, intraoperative fluid volume, daily liquid volume difference and infusion of human serum albumin were risk factors for perioperative heart failure in elderly hip fractures (c2=19.861, c2=7.075, c2=8.732, c2=25.504, c2=29.226, c2=45.825, c2=14.362, c2=6.662, c2=8.190, c2=7.216, c2=30.086, c2=10.122, c2=12.079, P<0.05). The logistic regression analysis showed that combined with more than 4 underlying diseases, cardiovascular disease, anemia, electrolyte imbalance, perioperative fluid intake, ASA classification were independent risk factors for perioperative heart failure (OR: 5.769, 95% CI: 1.212-36.243; OR: 9.576, 95% CI: 2.118-45.387; OR: 3.686, 95% CI: 1.313-10.349; OR: 6.584, 95% CI: 1.217-26.744; OR: 14.114, 95% CI: 5.021-42.342;OR: 6.012, 95% CI: 3.245-11.329). Conclusions Perioperative heart failure in hip fracture is the result of combination of multiple factors, perioperative risk assessment, early treatment for complications, surgical trauma reduction and postoperative fluid rehydration are the key to reduce perioperative heart failure.

参考文献/References:

1 谢岩, 徐静. 慢性心力衰竭的诊治进展综述 [J]. 中国疗养医学, 2016, 25(2): 134-136.
2 Harboun M, Dorenlot P, Cohen NA, et al. Impact of hip fracture, heart failure and weight loss on the risk of institutionalization of community-dwelling patients with dementia [J]. Int J Geriatr Psychiatry, 2008, 23(12): 1245-1252.
3 Carbone L, Buzková P, Fink HA, et al. Hip fractures and heart failure: findings from the Cardiovascular Health Study. Eur Heart [J]. 2010, 31(1): 77-84.
4 Menzies IB, Mendelson DA, Kates SL, et al. The impact of comorbidity on perioperative outcomes of hip fractures in a geriatric fracture model [J]. Geriatr Orthop Surg Rehabil, 2012, 3(3): 129-134.
5 陈炎, 陈亚蓓, 陶荣芳. 《2014中国心力衰竭诊断和治疗指南》解读 [J]. 中国实用内科杂志, 2014, S2: 69-73.
6 岳晓东, 张国强, 林峰. 老年髋部骨折围手术期并发症的临床分析 [J]. 中华保健医学杂志, 2015, 17(6): 443-445.
7 Tsai CH, Lin CL, Hsu HC, et al. Increased risk of coronary heart disease in patients with hip fracture: a nationwide cohort study [J]. Osteoporos Int, 2015, 26(6): 1849-1855.
8 苏鹏, 云才, 尤锡东. 不同年龄分组老年髋部骨折在围手术期治疗的研究 [J]. 实用骨科杂志, 2016, 22(5): 447-450.
9 Sathiyakumar V, Avilucea FR, Whiting PS, et al. Risk factors for adverse cardiac events in hip fracture patients: an analysis of NSQIP data [J]. Int Orthop, 2016, 40(3): 439-445.
10 何振东. 手术与非手术治疗老年髋部骨折的生存受益分析 [D]. 兰州: 兰州大学, 2016 .
11 Parker M, Johansen A. Hip fracture [J]. BMJ, 2006, 333(7557): 27-30.
12 张子安, 王英振. 老年髋部骨折的围手术期处理及康复治疗现状 [J]. 中国矫形外科杂志, 2016, 24(20): 1876-1880.
13 Yoshioka K, Matsue Y, Kagiyama N, et al. Recovery from hyponatremia in acute phase is associated with better in-hospital mortality rate in acute heart failure syndrome [J]. J Cardiol, 2016, 67(5): 406-411. 14 Sánchez-Torrijos J, Gudín-Uriel M, Nadal-Barangé M, et al. [Prognostic value of discharge hemoglobin level in patients hospitalized for acute heart failure] [J]. Rev Esp Cardiol, 2006, 59(12):1276-1282.
15 杨立辉, 安立琨, 柳伟, 等. 老年髋部骨折患者围术期特点及手术疗效的危险因素分析 [J]. 中华老年医学杂志, 2014, 33(5): 507-509.
16 Sharma K, Kass DA. Heart failure with preserved ejection fraction: mechanisms, clinical features, and therapies [J]. Circ Res, 2014, 115(1): 79-96.
17 Cullen MW, Gullerud RE, Larson DR, et al. Impact of heart failure on hip fracture outcomes: a population-based study. [J] Hosp Med. 2011, 6(9): 507-12. 
18 Molica F, Morel S, Kwak BR, et al. Adipokines at the crossroad between obesity and cardiovascular disease [J]. Thromb Haemost, 2015, 113(3): 553-566.
19 Michel JP, Klopfenstein C, Hoffmeyer P, et al. Hip fracture surgery: Is the pre-operative American Society of Anesthesiologists (ASA) score a predictor of functional outcome? [J]. Aging Clin Exp Res, 2002, 14(5): 389-394.
20 Felker GM, Adams KF, Gattis WA, et al. Anemia as a risk factor and therapeutic target in heart failure [J]. J Am Coll Cardiol, 2004, 44(5): 959-966.
21 胡永明, 陈建庆, 吴震, 等. 帕瑞昔布钠对下肢骨折内固定取出术后镇痛及应激反应的影响 [J]. 江苏医药, 2012, 38(3): 323-325.
22 Märdian S, Perka C, Schaser KD, et al. Cardiac disease and advanced age increase the mortality risk following surgery for periprosthetic femoral fractures. Bone Joint [J]. 2017, 99(7): 921-926.
23 张贵田, 潘爱群, 刘国海, 等. 两种补液方法院前急救治疗创伤性休克的临床研究 [J]. 中国全科医学, 2010, 13(21): 2363-2364.
24 桂凯. 限制补液量对择期腹部手术患者围术期各类并发症发生率影响 [J]. 中国实用医药, 2013, 8(8): 190-191.

相似文献/References:

[1]赵晨,商培洋,车凌宾,等.锁定钢板治疗老年肱骨近端骨折合并肩袖撕裂的疗效分析[J].中华老年骨科与康复电子杂志,2015,(01):22.
[2]吴斗,郝海虎,朱剑,等.老年髋部骨折术后谵妄的危险因素分析[J].中华老年骨科与康复电子杂志,2015,(01):34.
[3]高文双,曹建业,吴卫卫,等.墙壁拉力器训练对老年下腰背痛的疗效研究[J].中华老年骨科与康复电子杂志,2015,(01):39.
[4]姬晨妮,陈伟,朱燕宾,等.京津唐地区1 583例老年股骨转子间骨折流行病学特征分析[J].中华老年骨科与康复电子杂志,2015,(01):45.
[5]李石伦,鞠林林,陈伟,等.老年脊柱骨折的流行病学特征分析[J].中华老年骨科与康复电子杂志,2015,(01):50.
[6]杨延江 董天华 杜晨光 杨宗酉 陈伟 吕红芝 刘磊 孙家元 王海立 殷兵  刘勃 刘松 张英泽.2008 年至2012 年河北医科大学第三医院 老年踝关节损伤的流行病学研究[J].中华老年骨科与康复电子杂志,2015,(02):35.[doi:10.3877/cma.j.issn.2096-0263.2015.02 .007]
 Yang Yanjiang,Dong Tianhua,Du Chenguang,et al.Epidemiological analysis of elderly ankle injury in the Third Hospital of Hebei Medical University from 2008 through 2012[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2015,(01):35.[doi:10.3877/cma.j.issn.2096-0263.2015.02 .007]
[7]李梦远,陈宏 马元琛,廖俊星,等.老年髋部骨折内固定失败后补救性髋关节置换术的临床研究[J].中华老年骨科与康复电子杂志,2016,(02):81.[doi:10.3877/cma.j.issn.2096-0263.2016.02.004]
 Li Mengyuan,Chen Hong,Ma Yuanchen,et al.Clinical research of hip arthroplasty as a salvage treatment after reduction and fixation failure in the proximal femoral fracture[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2016,(01):81.[doi:10.3877/cma.j.issn.2096-0263.2016.02.004]
[8]高延征,张广泉,邢帅,等.经皮椎体成形术与经皮椎体后凸成形术治疗老年 Kümmell 病的对比研究[J].中华老年骨科与康复电子杂志,2016,(03):136.[doi:10.3877/cma.j.issn.2096-0263.2016.03.002]
 Gao Yanzheng,Zhang Guangquan,Xing Shuai,et al.Comparative analysis of percutaneous vertebroplasty and percutaneous kyphoplastyon in the treatment of the elderly with Kümmell disease[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2016,(01):136.[doi:10.3877/cma.j.issn.2096-0263.2016.03.002]
[9]于沂阳,刘勃,陈伟,等.2008—2012 年河北医科大学第三医院老年骨折流行病学特征分析[J].中华老年骨科与康复电子杂志,2016,(03):172.[doi:10.3877/cma.j.issn.2096-0263.2016.03.009]
 Yu Yiyang,Liu Bo,Chen Wei,et al.Epidemiological analysis of geratic fractures in the Third Affiliated Hospital to Hebei Medical University from 2008 to 2012[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2016,(01):172.[doi:10.3877/cma.j.issn.2096-0263.2016.03.009]
[10]李玉龙,翁习生,董玉雷.老年全膝关节置换术围手术期并发症影响因素的研究进展[J].中华老年骨科与康复电子杂志,2016,(03):177.[doi:10.3877/cma.j.issn.2096-0263.2016.03.010]
 Li Yulong,Weng Xisheng,Dong Yulei.Research progress of influence factors concerning perioperative complications of total knee arthroplasty in aged patients[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2016,(01):177.[doi:10.3877/cma.j.issn.2096-0263.2016.03.010]
[11]吕厚辰,唐佩福.老年髋部骨折患者死亡风险评价[J].中华老年骨科与康复电子杂志,2016,(02):109.[doi:10.3877/cma.j.issn.2096-0263.2016.02.009]
 Lyu Houchen,Tang Peifu..Advancement of mortality prediction of aged hip fracture patients[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2016,(01):109.[doi:10.3877/cma.j.issn.2096-0263.2016.02.009]
[12]陈述祥,刘彦,区文欢,等.老年髋部骨折术后肺部并发症的危险因素分析[J].中华老年骨科与康复电子杂志,2016,(04):239.[doi:10.3877/cma.j.issn.2096-0263.2016.04.009]
 Chen Shuxiang,Liu Yan,Ou Wenhuan,et al.Risk factor analysis for postoperative pulmonary complications in elderly hip fractures[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2016,(01):239.[doi:10.3877/cma.j.issn.2096-0263.2016.04.009]
[13]刘松 陈伟 朱燕宾 李彦森 殷兵 张飞 李佳 张英泽.2010—2011年中国东北和西北地区老年髋部骨折的流行病学对比[J].中华老年骨科与康复电子杂志,2017,(03):172.[doi:10.3877/cma.j.issn.2096-0263.2017.03.008]
 Liu Song,Chen Wei,Zhu Yanbin,et al.Epidemiological comparison of hip fractures in the elderly between northeast and northwest areas of China from 2010 to 2011[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2017,(01):172.[doi:10.3877/cma.j.issn.2096-0263.2017.03.008]
[14]王东,周君琳.老年髋部骨折术后早期负重的时机及其影响因素[J].中华老年骨科与康复电子杂志,2017,(05):257.[doi:10.3877/cma.j.issn.2096-0263.2017.05.001]
 Wang Dong,Zhou Junlin.The timing and influence factors of early postoperative weight-bearing in elderly hip fracture patients[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2017,(01):257.[doi:10.3877/cma.j.issn.2096-0263.2017.05.001]
[15]卢冰,王跃,刘攀,等.髓内钉及动力髋螺钉治疗老年稳定性股骨转子间骨折的比较[J].中华老年骨科与康复电子杂志,2017,(05):260.[doi:10.3877/cma.j.issn.2096-0263.2017.05.002]
 Lu Bing,Wang Yue,Liu Pan,et al.Comparison of the clinical efficacy between proximal femoral nail and DHS in the treatment of elderly patients with intertrochanteric fractures[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2017,(01):260.[doi:10.3877/cma.j.issn.2096-0263.2017.05.002]
[16]刘松,李佳,李石伦,等.中国华北和华东地区2010至2011年老年股骨转子间骨折流行病学对比分析[J].中华老年骨科与康复电子杂志,2018,(01):43.[doi:10.3877/cma.j.issn.2096-0263.2018.01.010]
 Liu Song,Li Jia,Li Shilun,et al.Epidemiological comparison of femoral intertrochanteric fractures in the elderly between northern and eastern China from 2010 to 2011[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2018,(01):43.[doi:10.3877/cma.j.issn.2096-0263.2018.01.010]
[17]张晟,余斌.个体化围手术期方案在高龄股骨转子间骨折治疗中的应用[J].中华老年骨科与康复电子杂志,2018,(03):132.[doi:10.3877/cma.j.issn.2096-0263.2018.03.002]
 Zhang Sheng,Yu Bin.The clinical experience of the perioperative management of intertrochanteric fracture with elderly highrisk patients[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2018,(01):132.[doi:10.3877/cma.j.issn.2096-0263.2018.03.002]
[18]张宇 秦晓东 许艺荠 谢文俊 胡军.老年股骨转子间骨折术后1年死亡率及危险因素分析[J].中华老年骨科与康复电子杂志,2018,(05):277.
 Zhang Yu,Qin Xiaodong,Xu Yiqi,et al.Risk factors related to mortality at one year after surgery for intertrochanteric fracture in the elderly[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2018,(01):277.
[19]王虎 李明 靳泽岳 连晓东 陈伟. 不同方法治疗老年股骨转子间合并转子下骨折的比较[J].中华老年骨科与康复电子杂志,2019,(03):135.[doi:DOI:10.3877/cma.j.issn.2096-0263.2019.003]
 Wang Hu,Chen Wei.. Comparative of different methods for the treatment of intertrochanteric-subtrochanteric fracture[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2019,(01):135.[doi:DOI:10.3877/cma.j.issn.2096-0263.2019.003]
[20]刘澍雨,朱伟民,刘雨微,等.快速康复外科理念在老年髋部骨折中的术前应用[J].中华老年骨科与康复电子杂志,2021,(01):60.[doi:10.3877/cma.j.issn.2096-0263.2021.01.011]
 Liu Shuyu,,et al.Preoperative preparation for enhanced recovery after surgery in elderly hip fractures[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2021,(01):60.[doi:10.3877/cma.j.issn.2096-0263.2021.01.011]

备注/Memo

备注/Memo:
基金项目:河北省2017年度医学科学研究重点课题计划(20171253)
更新日期/Last Update: 2018-01-31