[1]李涛,王英振,李玉龙,等.骨水泥与非骨水泥半髋关节置换治疗老年股骨颈骨折安全性的 Meta分析[J].中华老年骨科与康复电子杂志,2017,(02):109-115.[doi:10.3877/cma.j.issn.2096-0263.2017.02.008]
　Li Tao,Wang Yingzhen,Li Yulong,et al.Safety of cement and cementless hemiarthroplasty for femoral neck fractures in elderly patients: a meta- analysis[J].Chin J Geriatr Orthop Rehabil(Electronic Edition),2017,(02):109-115.[doi:10.3877/cma.j.issn.2096-0263.2017.02.008]
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骨水泥与非骨水泥半髋关节置换治疗老年股骨颈骨折安全性的 Meta分析()
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中华老年骨科与康复电子杂志[ISSN:1674-3911/CN:11-9292/R]

卷:
期数:
2017年02期
页码:
109-115
栏目:
Meta分析
出版日期:
2017-03-25

文章信息/Info

Title:
Safety of cement and cementless hemiarthroplasty for femoral neck fractures in elderly patients: a meta- analysis
作者:
李涛 1; 王英振 1; 李玉龙 2; 肖刻 2; 王磊 1; 翁习生 2
266003 青岛大学附属医院骨科 1；100730 北京协和医学院北京协和医院骨科 2
Author(s):
Li Tao1;  Wang Yingzhen1;  Li Yulong2;  Xiao Ke2;  Wang Lei1;  Weng Xisheng2
1Department of Orthopaedics, The Affiliated Hospital of Qingdao University, Qingdao 266003, China; 2Department of Orthopaedics, Peking Union Medical College Hospital, Peking Union Medical College, Beijing 100730, China
关键词:
股骨颈骨折;  股骨头;  关节成形术; 置换;  骨水泥;  Meta分析
Keywords:
Femur neck fractures;  Femur head;  Arthroplasty;  replacement;  Bone cements;  Meta-analysis
DOI:
10.3877/cma.j.issn.2096-0263.2017.02.008
文献标志码:
A
摘要:
目的 通过 Meta分析对骨水泥与非骨水泥半髋关节置换治疗老年股骨颈骨折的安全性进行评价。方法 计算机检索 PubMed、Cochrane Library、EMBase、万方数据库、维普中文科技期刊等数据库，英文检索词为“hemiarthroplasty”、“arthroplasty”、“replacement”，中文检索词为“股骨颈骨折”、“关节置换术”，由 2名评价者严格按照纳入及排除标准进行文献筛选，收集关于骨水泥与非骨水泥半髋关节置换治疗老年股骨颈骨折的随机对照研究，检索日期均为建库至 2015年 9月，提取相关数据后输入 RevMan 5.2软件进行统计学分析。本研究采用死亡率、并发症发生率、再手术率等指标的优势比对手术的安全性进行评价。结果 本研究共纳入随机对照研究 11篇，总样本量为 1 531例髋。Meta分析结果显示，骨水泥半髋关节置换术后假体相关并发症少（OR=0.17，95% CI：0.11～0.27，P＜0.001），在心脑血管并发症、全身并发症、局部并发症、术后死亡率和再手术率方面，两种置换方式比较差异无统计学意义。结论 与非骨水泥相比，骨水泥半髋关节置换假体具有相关并发症少等优点，同时不增加其他并发症、术后死亡率及再次手术率。
Abstract:
Objective To assess the safety of cement hemiarthroplasty and cementless hemiarthroplasty for femoral neck fractures in elderly patients through a mate- analysis. Methods Literatures about cement and cementless hemiarthroplasty published before December 2015 were identified through PubMed, Cochrane Library, EMBase, WANFANG and VIP databases. Key words were "femoral neck fracture" "hemiarthroplasty", randomized controlled trial about cement and cementless hemiarthroplasty were collected, relevant data were extracted and evaluated with Review Manager 5.2 for meta- analysis by two reviewers. Relative risk (OR) of mortality，the rate of complications and reoperation rate in the two groups were calculated. Results Eleven randomized controlled trials met the selection criteria involving 1531 hips. The meta- analysis showed that cement hemiarthroplasty can decrease the rate of complications related to prosthesis (OR=0.17, 95% CI: 0.11- 0.27, P<0.001), while there was no significant difference between two groups in cardiovascular and cerebrovascular complications, general complications, local complications, moralityandreoperationrate.Conclusion Compared to cementless hemiarthroplasty, cement hemiarthroplasty can achieve low complications related to the prothesis, meanwhile without increasing other complications rate, morality and reoperative rate.

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备注/Memo

备注/Memo:
基金项目：卫生部公益性行业科研专项项目（201302007）
更新日期/Last Update: 2017-04-01